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It is no wonder that now the latest idea is to merge prescription medications with the idea that with all the combination could have the miraculous results that they can so desperately want and perhaps need. Using two separate drugs to shed pounds can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight loss and the people who go through it one should err on the side of caution and permit the FDA do its job and demand some investigation be done so that the public is aware of the side effects and perils associated with the medications before we take them. Keep in mind that drug companies are in business to generate income and that they would say everything to keep people on their medications. Researchers discovered that participants investing in this drug to get a year, dropped excess weight within 4 weeks and have kept the weight off during the entire 56 weeks from the study. Contrave is really a combination from the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which can be made up of more than one active ingredient, which might make them more effective and safer. Combo-pilling could be the newest fad or even better the newest into the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular could be the fact that as of right now there aren't long term prescription slimming capsules that have been licensed by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug also can raise hypertension and pulse rate, and really should not be used in people who have a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise hypertension and pulse rate and must not used in patients with uncontrolled high blood pressure levels, as well as by you aren't heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients which has a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients towards the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. Approving a drug with this many potentially lethal negative effects is inconsistent using the mission statement from the FDA. The power with the drug manufacturing lobby is blatantly evident within the approval of several drugs requiring 'post-marketing' studies which might be clearly significant to overall drug safety in the US.