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Using two separate drugs to lose weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the those who go through it you ought to err along the side of caution and allow FDA do its job and demand some study be done so that the public understands the side effects and hazards of the medications before we drive them. Keep in mind that drug companies will be in business to generate money and that they would say everything to keep people on their medications. Researchers found out that participants using this drug for any year, dropped excess weight within a month and have kept the weight off throughout the 56 weeks of the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs that are made up of multiple active ingredient, which may make them far better and safer. Combo-pilling could be the newest fad or even better the newest into the future under scrutiny and so it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular is the fact that as of right now there are no long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug also can raise hypertension and heart rate, and must not be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must 't be used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients to the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking. 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