The National Nanotechnology Initiative has motivated substantial growth in nanoscience and nanotechnology research in the United States and beyond. One of the central goals of the National Nanotechnology Initiative is the development and education of future generations of nanoscience researchers. This Nano Focus provides a brief history of nanoscience education, including curricula that have been implemented successfully into secondary and college institutions, as described in the symposium “Integrating Nanoscience into the College and High School Classroom” at the 237th American Chemical Society National Meeting in March 2009.